This paper seeks to inform the discussion on what the price of HFO-1234yf (2,3,3,3-tetrafluoropropene) might be over the longer term when application and process patents have expired, economy of scale is achieved at production facilities using the most efficient processes, more producers are involved, and a fully competitive global market takes hold. The analysis focuses on the estimated costs of production based on one process currently in use, and a different process at a recently completed facility. We expect that long-term market prices will reflect broader factors of supply and demand. It is also possible over time that new or improved production processes will allow production of HFO-1234yf at lower costs and prices than estimated here.